New Pill-and-Infusion combo aims to tame rare blood cancer without chemo
NCT ID NCT07285590
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of two drugs, pirtobrutinib (a pill) and rituximab (an infusion), in 50 adults newly diagnosed with a slow-growing form of mantle cell lymphoma. The goal is to see if this drug pair can shrink or control the cancer without the need for standard chemotherapy. Participants will receive the treatment for several cycles, and researchers will track how many achieve complete remission after 6 cycles.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clínica Universidad Navarra
RECRUITINGMadrid, Madrid, 28027, Spain
Contact Email: •••••@•••••
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Clínica Universidad Navarra
RECRUITINGPamplona, Pamplona, 31008, Spain
Contact Email: •••••@•••••
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Hospital Clinic de Barcelona
RECRUITINGBarcelona, Barcelona, 08036, Spain
Contact Email: •••••@•••••
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Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITINGEl Palmar, Murcia, 30120, Spain
Contact Email: •••••@•••••
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Hospital Clínico de Valencia
RECRUITINGValencia, Valencia, 46010, Spain
Contact Email: •••••@•••••
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Hospital Costa del Sol
RECRUITINGMarbella, Málaga, 29603, Spain
Contact Email: •••••@•••••
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, Madrid, 28007, Spain
Contact Email: •••••@•••••
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Hospital Ramon y Cajal
RECRUITINGMadrid, Madrid, 28034, Spain
Contact Email: •••••@•••••
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, Barcelona, 08035, Spain
Contact Email: •••••@•••••
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, Madrid, 28041, Spain
Contact Email: •••••@•••••
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Hospital Universitario de Salamanca
RECRUITINGSalamanca, Salamanca, 37007, Spain
Contact Email: •••••@•••••
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Hospital Universitario y Politécnico La Fe
NOT_YET_RECRUITINGValencia, Valencia, 46026, Spain
Contact Email: •••••@•••••
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INSTITUT CATALÀ D'ONCOLOGIA (ICO). Hospital Germans Trias I Pujol.
NOT_YET_RECRUITINGBadalona, Barcelona, 08916, Spain
Contact Email: •••••@•••••
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Institut Català d'oncologia de L'Hospitalet (ICO-L'Hospitalet)
NOT_YET_RECRUITINGL'Hospitalet de Llobregat, Barcelona, 08908, Spain
Contact Email: •••••@•••••
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Instituto Português de Oncologia de Lisboa Francisco Gentil
RECRUITINGLisbon, Lisbon District, 1099-023, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Unidade Local De Saude De Santa Maria E.P.E.
NOT_YET_RECRUITINGLisbon, Lisbon District, 1649-028, Portugal
Contact Phone: •••-•••-•••• Email: •••••@•••••