New combo therapy aims to beat back tough blood cancer
NCT ID NCT06553872
First seen Nov 17, 2025 · Last updated Apr 25, 2026 · Updated 18 times
Summary
This study tests whether adding the targeted drug pirtobrutinib to standard CAR T-cell therapy can better control mantle cell lymphoma that has come back or stopped responding to treatment. About 60 adults will be randomly assigned to receive the drug before or after the cell infusion. The goal is to see if the combination keeps the cancer away longer and is safe.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford Cancer Center
NOT_YET_RECRUITINGStanford, California, 94305, United States
Contact Phone: •••-•••-••••
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Univ of Miami - Sylvester Comprehensive Cancer Center
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-••••
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Conditions
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