Can a simple exam replace needles for piriformis diagnosis?

NCT ID NCT07473349

Not yet recruiting Diagnosis Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to see if common physical exams and diagnostic criteria can accurately identify piriformis syndrome, a cause of buttock pain. Researchers will enroll 75 adults with gluteal pain and compare exam results to an ultrasound-guided lidocaine injection into the piriformis muscle. If pain drops by half after the injection, it confirms the syndrome. The goal is to find reliable, non-invasive ways to diagnose this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine
What this could lead to: If successful, this could lead to a reliable, non-invasive way to diagnose piriformis syndrome, reducing the need for injections.
What could go wrong: This is a small, early-stage study with only 75 participants. The injection reference standard may not be perfect, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

piriformis syndrome sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLUTEAL PAIN PIRIFORMIS SYNDROME

Contacts and locations

Locations

Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty

Istanbul, Turkey (Türkiye)

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