Ancient herb takes on fatty liver: new trial begins
NCT ID NCT07452744
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether a herbal extract called Picroliv can help people with non-alcoholic fatty liver disease (NAFLD). 170 adults with mild to moderate NAFLD will take either Picroliv or a placebo twice daily for 24 weeks, alongside standard lifestyle advice. The main goal is to see if Picroliv reduces liver fat measured by MRI.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Picroliv (a standardized extract from the plant Picrorhiza kurroa)
What this could lead to
If it works, this could provide a new treatment option for non-alcoholic fatty liver disease, potentially reducing liver fat and improving liver health.
What could go wrong
This is a mid-stage trial with only 170 participants, so results may not apply to everyone. The herbal extract may not prove more effective than placebo, and long-term safety is not yet established.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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All India Institute of Medical Sciences
Delhi, NEW DELHI, 110029, India
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Institute of Liver and Biliary Sciences
Vasant Kunj, NEW DELHI, 110070, India
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King Edward Memorial Hospital
Mumbai, Maharashtra, 400012, India
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King George 's Medical University
Chowk, Lucknow, 226003, India
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Nizam's Institute of Medical Sciences
Panjagutta, Hyderabad, 500082, India
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PGIMER
Chandigarh, Chandigarh, 160012, India