New device aims to seal brain aneurysms and prevent strokes

NCT ID NCT07143019

Recruiting now Disease control Sponsor: phenox Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 6 times

Summary

This study is testing a device called a flow modulator to treat wide-necked brain aneurysms. The device is placed inside the artery to redirect blood flow away from the aneurysm, helping it close off. Researchers will check if the device is safe and effective in 214 adults over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: p48 MW HPC and p64 MW HPC Flow Modulation Device
What this could lead to: If successful, this device could offer a safe and effective way to treat wide-necked brain aneurysms, reducing the risk of stroke or rupture.
What could go wrong: This is a single-arm trial without a comparison group, so results may be less definitive. Risks include stroke or neurological death from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aneurysm Bites and Stings brain aneurysm hemorrhagic stroke intracranial berry aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEURYSM, INTRACRANIAL BRAIN ANEURYSM FUSIFORM ANEURYSM HEMORRHAGIC STROKE SACCULAR ANEURYSM

Contacts and locations

Locations

Advocate Lutheran General Hospital
RECRUITING

Park Ridge, Illinois, 60068, United States
Baptist Health Research Institute
RECRUITING

Jacksonville, Florida, 32207, United States
Barrow Neurological Institute
RECRUITING

Phoenix, Arizona, 85013, United States
East Carolina University Health Medical Center
RECRUITING

Greenville, North Carolina, 27834, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
NewYork-Presbyterian / Weill Cornell Medical Center
RECRUITING

New York, New York, 10065, United States
North Shore University Hospital - Northwell Health
RECRUITING

Manhasset, New York, 11030, United States
Northwestern Medicine
RECRUITING

Chicago, Illinois, 60611, United States
Oregon Health & Science University Hospital (OHSU) / Oregon Stroke Center
RECRUITING

Portland, Oregon, 97239, United States
Piedmont Atlanta Hospital
RECRUITING

Atlanta, Georgia, 30309, United States
Stony Brook University Hospital
RECRUITING

Stony Brook, New York, 11794, United States
Swedish Medical Research Center
RECRUITING

Englewood, Colorado, 80113, United States
The University of Oklahoma
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Tufts Medical Center
RECRUITING

Boston, Massachusetts, 02111, United States
UBNS
RECRUITING

Buffalo, New York, 14203, United States
UCSF Medical Center
RECRUITING

San Francisco, California, 94143, United States
University of Colorado Anschutz
RECRUITING

Aurora, Colorado, 80045, United States
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Washington - Harborview Medical Center
RECRUITING

Seattle, Washington, 98104, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
WashU Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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