New device aims to seal brain aneurysms and prevent strokes

NCT ID NCT07143019

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a device called a flow modulator to treat wide-necked brain aneurysms. The device is placed inside the artery to redirect blood flow away from the aneurysm, helping it close off. Researchers will check if the device is safe and effective in 214 adults over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

p48 MW HPC and p64 MW HPC Flow Modulation Device

What this could lead to

If successful, this device could offer a safe and effective way to treat wide-necked brain aneurysms, reducing the risk of stroke or rupture.

What could go wrong

This is a single-arm trial without a comparison group, so results may be less definitive. Risks include stroke or neurological death from the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm Bites and Stings brain aneurysm hemorrhagic stroke intracranial berry aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Advocate Lutheran General Hospital

    RECRUITING

    Park Ridge, Illinois, 60068, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baptist Health Research Institute

    RECRUITING

    Jacksonville, Florida, 32207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • East Carolina University Health Medical Center

    RECRUITING

    Greenville, North Carolina, 27834, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NewYork-Presbyterian / Weill Cornell Medical Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • North Shore University Hospital - Northwell Health

    RECRUITING

    Manhasset, New York, 11030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health & Science University Hospital (OHSU) / Oregon Stroke Center

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact

  • Piedmont Atlanta Hospital

    RECRUITING

    Atlanta, Georgia, 30309, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stony Brook University Hospital

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Swedish Medical Research Center

    RECRUITING

    Englewood, Colorado, 80113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The University of Oklahoma

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UBNS

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • UCSF Medical Center at Mount Zion

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Anschutz

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington - Harborview Medical Center

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • WashU Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••