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Bed cycling may stop muscle wasting in critically ill patients

NCT ID NCT07017517

Recruiting now Knowledge-focused Sponsor: University of Chile Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding servo-assisted bed cycling to standard physical therapy can reduce muscle breakdown in critically ill patients with sepsis. Researchers will measure inflammation and muscle damage markers in 24 participants over 7 days. The goal is to understand if physical therapy can calm a specific inflammatory pathway (NLRP3) and prevent critical illness myopathy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
servo-assisted cycling device (Motomed Letto®) and standard physiotherapy
What this could lead to
If it works, this could point toward a simple, drug-free way to prevent severe muscle loss in ICU patients.
What could go wrong
This is a very small, early-stage study (24 people) focused on biological markers, not yet on patient outcomes. The results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute quadriplegic myopathy muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS MYOPATHY

Contacts and locations

Locations

  • Clínica INDISA

    RECRUITING

    Santiago, Metropolitan Region, 7520440, Chile

  • Hospital de Urgencia Asistencia Pública (HUAP)

    RECRUITING

    Santiago, Metropolitan Region, 8330075, Chile

  • University of Chile

    RECRUITING

    Santiago, Metropolitan Region, 8380453, Chile

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