Bed cycling may stop muscle wasting in critically ill patients
NCT ID NCT07017517
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding servo-assisted bed cycling to standard physical therapy can reduce muscle breakdown in critically ill patients with sepsis. Researchers will measure inflammation and muscle damage markers in 24 participants over 7 days. The goal is to understand if physical therapy can calm a specific inflammatory pathway (NLRP3) and prevent critical illness myopathy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
servo-assisted cycling device (Motomed Letto®) and standard physiotherapy
What this could lead to
If it works, this could point toward a simple, drug-free way to prevent severe muscle loss in ICU patients.
What could go wrong
This is a very small, early-stage study (24 people) focused on biological markers, not yet on patient outcomes. The results may not lead to a proven treatment.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clínica INDISA
RECRUITINGSantiago, Metropolitan Region, 7520440, Chile
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital de Urgencia Asistencia Pública (HUAP)
RECRUITINGSantiago, Metropolitan Region, 8330075, Chile
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Chile
RECRUITINGSantiago, Metropolitan Region, 8380453, Chile