Engineered immune cells take aim at stubborn childhood cancer

NCT ID NCT07007117

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 29 times

Summary

This early-phase trial tests a new treatment for children with neuroblastoma that has come back or is hard to treat. The therapy uses the patient's own immune cells, modified to recognize and attack cancer cells carrying a protein called PHOX2B. The main goal is to find a safe dose and monitor side effects in about 38 participants aged 1 and older.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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