Light therapy combo targets deadly bile duct cancer in new trial

NCT ID NCT07398339

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing a new approach for people with advanced bile duct cancer that has caused a blockage. The treatment combines a light-activated drug (sodium porphyrin) with standard chemotherapy (gemcitabine and cisplatin). The goal is to see if this combination can help patients live longer and control the cancer. The study will enroll 30 participants and measure survival at 6 months as the main outcome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium porphyrin injection (photosensitizer) used in photodynamic therapy, plus gemcitabine and cisplatin chemotherapy

What this could lead to

If successful, this could offer a new treatment option to help people with advanced bile duct cancer live longer and control the disease.

What could go wrong

This is an early phase 2 trial with only 30 people, so results may not apply to everyone. The treatment may cause side effects like light sensitivity and chemotherapy-related toxicity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms extrahepatic bile duct carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • No. 266, Trumpet Vine Road

    RECRUITING

    Shanghai, Pudong New Area, 200120, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••