Can a stitch in time prevent a stroke? new device aims to close heart holes
NCT ID NCT07726927
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests a new suture system designed to close a patent foramen ovale (PFO), a small hole in the heart that can increase stroke risk. Researchers will compare the new device to an existing occluder in about 244 adults aged 18 to 65 with moderate-to-large PFOs. The goal is to see if the suture system is as safe and effective at sealing the hole one year after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a new suture system for closing patent foramen ovale (PFO)
- What this could lead to
- If successful, this could offer an alternative to the standard PFO occluder device, potentially reducing stroke risk in people with PFO.
- What could go wrong
- This is an early-stage trial comparing a new device to an existing one. The new suture system may not be as effective or safe as the standard occluder.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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