New combo therapy targets Hard-to-Treat prostate cancer

NCT ID NCT05367440

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tests a new drug (AZD5305) combined with standard hormone therapies in people with metastatic prostate cancer that has spread. The goal is to check safety, how the drug moves through the body, and early signs of effectiveness. About 174 adults whose cancer has spread and who are candidates for hormone therapy will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Detroit, Michigan, 48201, United States

  • Research Site

    Detroit, Michigan, 48202, United States

  • Research Site

    Syracuse, New York, 13210, United States

  • Research Site

    Myrtle Beach, South Carolina, 29572, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Houston, Texas, 77094, United States

  • Research Site

    Camperdown, 2050, Australia

  • Research Site

    Darlinghurst, 2010, Australia

  • Research Site

    East Melbourne, 3002, Australia

  • Research Site

    Heidelberg, 3084, Australia

  • Research Site

    Melbourne, 3004, Australia

  • Research Site

    St Leonards, 2065, Australia

  • Research Site

    Candiolo, 10060, Italy

  • Research Site

    Milan, 20133, Italy

  • Research Site

    Orbassano, 10043, Italy

  • Research Site

    Padova, 35128, Italy

  • Research Site

    Cambridge, CB2 0QQ, United Kingdom

  • Research Site

    Glasgow, G12 0YN, United Kingdom

  • Research Site

    Manchester, M20 4BX, United Kingdom

  • Research Site

    Plymouth, PL6 8DH, United Kingdom

Conditions

Explore the condition pages connected to this study.