Brain scans reveal hidden protein changes in alcohol withdrawal

NCT ID NCT06795581

Recruiting now Knowledge-focused Sponsor: National Institute of Mental Health (NIMH) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a brain protein called PDE4B in people with alcohol use disorder. Researchers want to see if levels of this protein change during alcohol withdrawal and after a few weeks of not drinking. The study involves 30 adults who will have two PET brain scans and possibly an MRI. The goal is to better understand the brain's role in alcohol use disorder, which could lead to improved treatments in the future.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••