One-Size-Fits-All diet may fail seniors: new study aims to personalize nutrition
NCT ID NCT06163794
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at why people aged 60-75 respond differently to the same foods. Researchers will give 250 participants different test meals and track their blood sugar responses. The goal is to understand how factors like age, sex, gut bacteria, and lifestyle affect metabolism, which could lead to personalized nutrition advice for healthy aging.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nutritional postprandial test (test meals)
- What this could lead to
- If successful, this could lead to personalized dietary recommendations that help older adults maintain better metabolic health as they age.
- What could go wrong
- This is an early-stage observational study, not a treatment trial. It aims to understand variability, not to prove a specific intervention works. Results may not lead to immediate practical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \- Subject with grip strength (assessed with a dynamometer) ≥16kg for women and ≥26 kg for men. * 21 ≤ BMI ≤35 * Participant living in a rural or peri-urban area or city dweller, according to the population density grid of the Territorial Observatory (categories 3, 2 or 1 respectively). * Cognitively able to perform tests and answer questionnaires according to the judgment of the recruiting doctor and on the basis of the Mini-Mental State Examination (MMSE) * Available to carry out the entire protocol * Biological assessment considered by the investigator as compatible with participation in the study, * Subject agreeing to give written consent, and registration in the national file of volunteers who lend themselves to research * Person subject to a social security system. Exclusion Criteria: * \- Diabetes treated * Sub-acute pathology (flu, gastroenteritis, bacterial infection, etc.) or trauma (fracture, surgical intervention, etc.) in the 30 days preceding inclusion. * Hepatocellular insufficiency, * Heart failure with decompensation, * Renal insufficiency (clearance \<30 ml/min) * Chronic anti-inflammatory treatment, long-term corticosteroid therapy \> 1 month, infiltrations * Antibiotic treatment within 30 days prior to recruitment * Progressive pathology at the time of inclusion (cancer, etc.) * Gastrointestinal pathology deemed incompatible with the protocol * Eating habits incompatible with the protocol (allergies, test food intolerances/aversions, vegan diets, ketogenic diets, etc.) * Unstabilized thyroid diseases * Intense physical activity (activity causing shortness of breath and sweating) \> 10 hours per week * Person who is in a period of exclusion on the National File of Healthy Volunteers * Subject presenting a psychiatric pathology or cognitive disorders making them incapable of giving informed consent. * Subject under guardianship, curatorship, deprived of freedoms or under the protection of justice
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre de Recherche en Odontologie Clinique, Faculté de Chirurgie Dentaire
RECRUITINGClermont-Ferrand, 63100, France
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Pic / Cic-Inserm 1405
RECRUITINGClermont-Ferrand, France, 63000, France
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Plateforme d'Exploration de la Mobilité (CHU Clermont-Ferrand)
RECRUITINGClermont-Ferrand, 63009, France