Blood test guides chemo choice in cancer trial

NCT ID NCT02135042

Ongoing Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

Summary

This study is testing a personalized approach to treat nasopharyngeal cancer, a type of head and neck cancer linked to the Epstein-Barr virus. All participants first receive standard radiation and chemotherapy. Afterward, their treatment is customized based on whether a specific virus marker is still detectable in their blood. The goal is to see if this tailored strategy helps control the cancer better or allows some people to safely skip extra chemotherapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Ascension Saint Mary's Hospital

Saginaw, Michigan, 48601, United States
Ascension Saint Michael's Hospital

Stevens Point, Wisconsin, 54481, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494, United States
Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Baptist MD Anderson Cancer Center

Jacksonville, Florida, 32207, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
California Pacific Medical Center-Pacific Campus

San Francisco, California, 94115, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Centro Comprensivo de Cancer de UPR

San Juan, 00927, Puerto Rico
Chang Gung Hospital-Lin Kou Medical Center

Taoyuan District, 33333, Taiwan
Chinese University of Hong Kong-Prince of Wales Hospital

Shatin, Hong Kong, China
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
City of Hope South Pasadena

South Pasadena, California, 91030, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Cancer Center Mansfield

Mansfield, Ohio, 44906, United States
Cleveland Clinic Cancer Center Strongsville

Strongsville, Ohio, 44136, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Cleveland Clinic Wooster Family Health and Surgery Center

Wooster, Ohio, 44691, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Delbert Day Cancer Institute at PCRMC

Rolla, Missouri, 65401, United States
Diagnostic and Treatment Center

Weston, Wisconsin, 54476, United States
Emory Proton Therapy Center

Atlanta, Georgia, 30308, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fresno Cancer Center

Fresno, California, 93720, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Geisinger Cancer Services-Pottsville

Pottsville, Pennsylvania, 17901, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Oncology-Lewisburg

Lewisburg, Pennsylvania, 17837, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
HSHS Sacred Heart Hospital

Eau Claire, Wisconsin, 54701, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Inova Fairfax Hospital

Falls Church, Virginia, 22042, United States
Inova Schar Cancer Institute

Fairfax, Virginia, 22031, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada
John H Stroger Jr Hospital of Cook County

Chicago, Illinois, 60612, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Dublin

Dublin, California, 94568, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Oakland-Broadway

Oakland, California, 94611, United States
Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, California, 95670, United States
Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910, United States
Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016, United States
Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Legacy Salmon Creek Hospital

Vancouver, Washington, 98686, United States
Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
M D Anderson Cancer Center

Houston, Texas, 77030, United States
Maimonides Medical Center

Brooklyn, New York, 11219, United States
Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McGill University Department of Oncology

Montreal, Quebec, H2W 1S6, Canada
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
McKee Medical Center

Loveland, Colorado, 80539, United States
McLaren Cancer Institute-Bay City

Bay City, Michigan, 48706, United States
McLaren Cancer Institute-Central Michigan

Mount Pleasant, Michigan, 48858, United States
McLaren Cancer Institute-Clarkston

Clarkston, Michigan, 48346, United States
McLaren Cancer Institute-Flint

Flint, Michigan, 48532, United States
McLaren Cancer Institute-Lapeer Region

Lapeer, Michigan, 48446, United States
McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043, United States
McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States
McLaren-Port Huron

Port Huron, Michigan, 48060, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Medical Center

Modesto, California, 95355, United States
Memorial Medical Center

Springfield, Illinois, 62781, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Sleepy Hollow

Sleepy Hollow, New York, 10591, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mid-Michigan Physicians-Lansing

Lansing, Michigan, 48912, United States
Mills-Peninsula Medical Center

Burlingame, California, 94010, United States
Minnesota Oncology - Burnsville

Burnsville, Minnesota, 55337, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, 10032, United States
National Cancer Centre Singapore

Singapore, 169610, Singapore
National Taiwan University Hospital

Taipei, 100, Taiwan
Naval Medical Center - Portsmouth

Portsmouth, Virginia, 23708-2197, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
New York Proton Center

New York, New York, 10035, United States
New York-Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
North Coast Cancer Care

Sandusky, Ohio, 44870, United States
North Colorado Medical Center

Greeley, Colorado, 80631, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
Northwestern University

Chicago, Illinois, 60611, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Palo Alto Medical Foundation Health Care

Palo Alto, California, 94301, United States
Palo Alto Medical Foundation-Sunnyvale

Sunnyvale, California, 94086, United States
Pamela Youde Nethersole Eastern Hospital

Chai Wan, Hong Kong
Parker Adventist Hospital

Parker, Colorado, 80138, United States
Peter MacCallum Cancer Centre

Melbourne, Victoria, 3000, Australia
Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615, United States
Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605, United States
Prisma Health Cancer Institute - Greer

Greer, South Carolina, 29650, United States
Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672, United States
Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Radiation Oncology Centers of Nevada Central

Las Vegas, Nevada, 89106, United States
Radiation Oncology Centers of Nevada Southeast

Las Vegas, Nevada, 89119, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Renown Regional Medical Center

Reno, Nevada, 89502, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Riverton Hospital

Riverton, Utah, 84065, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Rush - Copley Medical Center

Aurora, Illinois, 60504, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Rutgers New Jersey Medical School

Newark, New Jersey, 07101, United States
SCL Health Cancer Centers of Colorado - Lutheran Medical Center

Golden, Colorado, 80401, United States
SCL Health Lutheran Medical Center

Wheat Ridge, Colorado, 80033, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint George Regional Medical Center

St. George, Utah, 84770, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint Joseph Mercy Canton

Canton, Michigan, 48188, United States
Saint Joseph Mercy Hospital

Ann Arbor, Michigan, 48106, United States
Saint Joseph Mercy Oakland

Pontiac, Michigan, 48341, United States
Saint Mary's Regional Medical Center

Reno, Nevada, 89503, United States
Sandra L Maxwell Cancer Center

Cedar City, Utah, 84720, United States
Singh and Arora Hematology Oncology PC

Flint, Michigan, 48532, United States
Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
South Sacramento Cancer Center

Sacramento, California, 95823, United States
Sparrow Hospital

Lansing, Michigan, 48912, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
Sun Yat-sen University Cancer Center

Guangzhou, 510060, China
Sutter Cancer Centers Radiation Oncology Services-Auburn

Auburn, California, 95603, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Cameron Park, California, 95682, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville

Roseville, California, 95661, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville

Vacaville, California, 95687, United States
Sutter Medical Center Sacramento

Sacramento, California, 95816, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Cancer Center of Hawaii-Pali Momi

‘Aiea, Hawaii, 96701, United States
The Kirklin Clinic at Acton Road

Birmingham, Alabama, 35243, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
Tom Baker Cancer Centre

Calgary, Alberta, T2N 4N2, Canada
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCSF Medical Center-Mission Bay

San Francisco, California, 94158, United States
UCSF Medical Center-Mount Zion

San Francisco, California, 94115, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Rochester

Rochester, New York, 14642, United States
University of Wisconsin Carbone Cancer Center

Madison, Wisconsin, 53792, United States
Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
Wesley Medical Center

Wichita, Kansas, 67214, United States
Yale University

New Haven, Connecticut, 06520, United States
Zhongshan Hospital Fudan University

Guangdong Province, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.

EPSTEIN-BARR VIRUS INFECTION STAGE II NASOPHARYNGEAL CARCINOMA STAGE III NASOPHARYNGEAL CARCINOMA STAGE IVA NASOPHARYNGEAL CARCINOMA STAGE IVB NASOPHARYNGEAL CARCINOMA