Brain tumor samples used to tailor drug cocktails in recurrent glioma trial

NCT ID NCT05532397

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a new way to choose drug combinations for people with recurrent high-grade astrocytic glioma, a type of aggressive brain cancer. Researchers take a sample of the tumor, grow it in the lab, and test many drug combinations to find the best one for that patient. The goal is to see if this personalized approach can improve how long patients live without the cancer growing. Only 10 participants will be enrolled in this early-stage trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

personalized drug combinations selected via QPOP platform

What this could lead to

If successful, this approach could help doctors choose more effective drug combinations for individual patients with recurrent brain cancer, potentially improving survival.

What could go wrong

This is a very early, small study (10 participants) testing a new method. The personalized combinations may not work better than standard treatments, and the platform may not be feasible for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GLIOMA, ASTROCYTIC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

astrocytic tumor astrocytoma (excluding glioblastoma) high grade astrocytic tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology-Oncology, National University Hospital

    RECRUITING

    Singapore, 119074, Singapore

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ng Teng Fong General Hospital

    NOT_YET_RECRUITING

    Singapore, 609606, Singapore

    Contact Phone: •••-•••-••••

    Contact