Custom cancer vaccine tested in early safety trial

This early-stage study tested whether a personalized vaccine, made from a patient's own tumor, could be safely created and given to people with advanced cancers that no longer respond to standard treatments. The vaccine was combined with an immunotherapy drug (pembrolizumab) to try to boost the body's immune system to fight the cancer. The main goal was to check for safety and see if the vaccine triggered an immune response, not to cure the disease.