One-of-a-Kind drug trial targets rare genetic brain disease

NCT ID NCT07221760

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a custom-made genetic medicine (called an antisense oligonucleotide) designed for one person with dentatorubral-pallidoluysian atrophy (DRPLA), a rare inherited brain disorder. The treatment aims to reduce seizures and improve quality of life. Only one participant is enrolled, and the study tracks changes in seizure activity and caregiver burden over two years.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dell Children's

    Austin, Texas, 78723, United States

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