New drug duo aims to wipe out stomach cancer before surgery

NCT ID NCT07477444

First seen Mar 19, 2026 · Last updated Apr 28, 2026 · Updated 3 times

Summary

This study tests whether adding two targeted drugs (zanidatamab and tislelizumab) to standard chemotherapy can completely eliminate HER2-positive gastroesophageal cancer before surgery. About 29 adults with operable, locally advanced cancer will receive the combination before and after tumor removal. The main goal is to see if more patients have no cancer left in the surgical sample compared to historical rates.

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