New drug cocktail targets tough lung cancer before and after surgery

NCT ID NCT07472478

First seen Mar 19, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests whether giving a combination of targeted drugs and chemotherapy before and after surgery can improve outcomes for people with a specific genetic subtype of lung cancer (KRAS G12C mutation). About 32 adults with stage IB to IIIB lung cancer that can be removed will receive the drugs glesorasib, ivonescimab, and chemotherapy. The main goal is to see how many patients have no cancer cells left in their removed tissue.

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