Scientists to create first cell atlas of gum healing around implants
NCT ID NCT07279090
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will create a detailed map of how gum tissue heals around dental implants. Researchers will place a tiny healing cap on the implant and collect small gum samples at 4 days, 2 weeks, and 8-10 weeks after placement. Using advanced genetic analysis, they will track which cells are active and how they interact during healing. The goal is to understand the healing process better and find ways to prevent implant infections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Healing abutment (micro device placed on dental implant)
- What this could lead to
- If successful, this could identify key factors that improve gum healing around dental implants and help prevent implant infections.
- What could go wrong
- This is a very small, early-stage observational study (5 participants) focused on understanding biology, not testing a treatment. Results may not lead to direct clinical benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 5 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: 18-65 years * Healthy individuals without chronic medical conditions or severe systemic diseases * Able to comply with study requirements (e.g., follow-up visits) * No history of periodontal disease or active infection * Already completed four or more implant placements in the posterior tooth region * Adequate gingival thickness to allow for sampling and proper healing Exclusion Criteria: * Individuals with systemic conditions that affect wound healing (e.g., diabetes, immunosuppressive therapy) * Smoking or alcohol abuse * Pregnant or breastfeeding women * History of severe allergic reactions to implant materials * Participation in another clinical study at the same time
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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School and Hospital of Stomatology, Fujian Medical University
Fuzhou, Fujian, 350004, China
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