New drug combo shows promise for head and neck cancer patients who Can't take chemo
NCT ID NCT04533750
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 30 times
Summary
This early-stage trial tests a drug called peposertib combined with radiation therapy for people with advanced head and neck cancer who cannot take the standard chemo drug cisplatin. The study aims to find the safest dose and see if the combination helps control the cancer. About 21 adults with stage 3 or 4 cancer of the mouth, throat, or voice box are taking part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Banner University Medical Center - Tucson
Tucson, Arizona, 85719, United States
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Carle Cancer Center
Urbana, Illinois, 61801, United States
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Carle Physician Group-Effingham
Effingham, Illinois, 62401, United States
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Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938, United States
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Carle at The Riverfront
Danville, Illinois, 61832, United States
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Emory University Hospital Midtown
Atlanta, Georgia, 30308, United States
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Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Highland Hospital
Rochester, New York, 14620, United States
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Inova Schar Cancer Institute
Fairfax, Virginia, 22031, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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NYU Langone Hospital - Long Island
Mineola, New York, 11501, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Providence Portland Medical Center
Portland, Oregon, 97213, United States
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Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, 57104, United States
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Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134, United States
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Stanford Cancer Institute Palo Alto
Palo Alto, California, 94304, United States
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The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of Arizona Cancer Center-North Campus
Tucson, Arizona, 85719, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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University of Rochester
Rochester, New York, 14642, United States
Conditions
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