Old drug, new hope? pentoxifylline trial targets jaundice
NCT ID NCT06944704
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 2 trial tested whether the drug pentoxifylline can help people with jaundice caused by liver or bile duct problems. 45 adults took 400 mg of pentoxifylline twice daily for 3 months, alongside standard care. Researchers measured changes in antioxidant levels, inflammation, and liver function to see if the drug improves bilirubin and liver health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pentoxifylline
What this could lead to
If it works, this could point toward a new way to reduce jaundice and improve liver function in people with liver or bile duct problems.
What could go wrong
This is a small, early-phase trial with only 45 people, so results may not apply to everyone. Pentoxifylline can cause side effects like nausea or bleeding risk.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Pharmacy, Tanta University
Tanta, 31111, Egypt