Pill vs. needle: can a daily penicillin pill prevent heart damage in kids?

NCT ID NCT05693545

First seen Mar 20, 2026 · Last updated May 17, 2026 · Updated 10 times

Summary

This study looks at whether taking penicillin twice a day by mouth is as good as getting a monthly shot to stop rheumatic heart disease from getting worse in children aged 5 to 17. The trial involves over 1,000 children with early signs of heart valve damage. If oral penicillin works just as well, it could make prevention easier and more comfortable for kids and families.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Uganda Heart Institute

    Kampala, Uganda, Uganda

Conditions

Explore the condition pages connected to this study.