Pill vs. needle: can a daily penicillin pill prevent heart damage in kids?

NCT ID NCT05693545

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether taking penicillin twice a day by mouth works as well as getting a penicillin shot every month to stop latent rheumatic heart disease from getting worse. About 1,000 children aged 5 to 17 with early signs of the disease are taking part. The goal is to find a simpler, less painful way to protect their hearts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatic heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Uganda Heart Institute

    Kampala, Uganda, Uganda