New drug duo offers hope for hard-to-treat vulvar cancer

NCT ID NCT05903833

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether two drugs, pembrolizumab and lenvatinib, can shrink tumors in people with vulvar cancer that has come back, spread, or is too advanced for surgery or radiation. About 42 participants will receive the combination. The main goal is to see how many have their tumors shrink or disappear within 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

vulva cancer vulvar carcinoma vulvar squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hochtaunus-Kliniken Bad Homburg

    RECRUITING

    Bad Homburg, Germany

  • KEM Kliniken Essen-Mitte

    RECRUITING

    Essen, Germany

  • Klinikum Hanau GmbH

    RECRUITING

    Hanau, Germany

  • Klinikum der Universität München, LMU

    RECRUITING

    München, Germany

  • University Hospital

    RECRUITING

    Tübingen, Germany

  • University Hospital Hamburg

    RECRUITING

    Hamburg, Germany

  • Universitätsklinikum Augsburg

    RECRUITING

    Augsburg, Germany

  • Universitätsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, Germany

  • Universitätsklinikum Düsseldorf

    RECRUITING

    Düsseldorf, Germany

  • Universitätsklinikum Essen

    RECRUITING

    Essen, Germany

  • Universitätsklinikum Mannheim

    RECRUITING

    Manheim, Germany

  • Universitätsklinikum Münster

    RECRUITING

    Münster, Germany

  • Universitätsmedizin Göttingen

    RECRUITING

    Göttingen, Germany

  • Universitätsmedizin Mainz

    RECRUITING

    Mainz, Germany

  • ZAGO - Zentrum für ambulante gynäkologische Onkologie

    NOT_YET_RECRUITING

    Krefeld, Germany