Double-Drug attack shows promise against advanced skin cancer

NCT ID NCT04889118

First seen Dec 31, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tested whether adding lenvatinib to pembrolizumab works better than pembrolizumab alone for people with advanced melanoma that cannot be removed by surgery. The trial included 131 Chinese participants who had not received prior treatment for their advanced disease. Researchers measured how long participants lived without their cancer worsening and overall survival.

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Contacts and locations

Locations

  • Beijing Cancer Hospital (0601)

    Beijing, Beijing Municipality, 100036, China

  • Fudan University Shanghai Cancer Center ( Site 0607)

    Shanghai, Shanghai Municipality, 200032, China

  • Fujian Provincial Cancer Hospital ( Site 0612)

    Fuzhou, Fujian, 350014, China

  • Henan Cancer Hospital ( Site 0610)

    Zhengzhou, Henan, 450003, China

  • Nanjing Drum Tower Hospital (0609)

    Nanjing, Jiangsu, 210008, China

  • Sir Run Run Shaw Hospital (0605)

    Hangzhou, Zhejiang, 310018, China

  • Sun Yat-Sen University Cancer Center (0602)

    Guangzhou, Guangdong, 510000, China

  • The First Hospital Of Jilin University (0603)

    Changchun, Jilin, 130021, China

  • Tianjin Medical University Cancer Institute & Hospital (0606)

    Tianjin, Tianjin Municipality, 300060, China

  • Yunnan Cancer Hospital (0604)

    Kunming, Yunnan, 430030, China

  • Zhejiang Cancer Hospital ( Site 0608)

    Hangzhou, Zhejiang, 310022, China

Conditions

Explore the condition pages connected to this study.