New combo therapy shows promise for advanced skin cancer patients

NCT ID NCT04889118

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding lenvatinib to pembrolizumab works better than pembrolizumab alone for people with advanced melanoma who haven't had prior treatment. It involved 131 Chinese participants with stage III or IV melanoma that could not be removed by surgery. The goal was to see if the combination helps delay cancer growth or improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autosomal dominant Parkinson disease 4 melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hospital (0601)

    Beijing, Beijing Municipality, 100036, China

  • Fudan University Shanghai Cancer Center ( Site 0607)

    Shanghai, Shanghai Municipality, 200032, China

  • Fujian Provincial Cancer Hospital ( Site 0612)

    Fuzhou, Fujian, 350014, China

  • Henan Cancer Hospital ( Site 0610)

    Zhengzhou, Henan, 450003, China

  • Nanjing Drum Tower Hospital (0609)

    Nanjing, Jiangsu, 210008, China

  • Sir Run Run Shaw Hospital (0605)

    Hangzhou, Zhejiang, 310018, China

  • Sun Yat-Sen University Cancer Center (0602)

    Guangzhou, Guangdong, 510000, China

  • The First Hospital Of Jilin University (0603)

    Changchun, Jilin, 130021, China

  • Tianjin Medical University Cancer Institute & Hospital (0606)

    Tianjin, Tianjin Municipality, 300060, China

  • Yunnan Cancer Hospital (0604)

    Kunming, Yunnan, 430030, China

  • Zhejiang Cancer Hospital ( Site 0608)

    Hangzhou, Zhejiang, 310022, China