New drug combo aims to control lymphoma without chemo side effects

NCT ID NCT04268277

First seen Feb 28, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This study tested a chemotherapy-free combination of pembrolizumab and rituximab in 22 people with marginal zone lymphoma (a slow-growing blood cancer). The goal was to see if this approach could control the disease as well as standard chemo but with fewer side effects. The trial was terminated early, so results are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MARGINAL ZONE LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Brüderkrankenhaus St. Josef, Klinik für Hämatologie und Onkologie

    Paderborn, 33098, Germany

  • Charité Universitätsmedizin Berlin; Hämatologie - Onkologie - Tumorimmunologie

    Berlin, 12200, Germany

  • Gemeinschaftspraxis Dr. med. Johannes Mohm, Dr. med. Gabriele Prange-Krex

    Dresden, 01307, Germany

  • Gemeinschaftspraxis für Hämatologie und Onkologie

    Münster, 48149, Germany

  • Kliniken Maria Hilf GmbH; Klinik für Hämatologie, Onkologie und Gastroenterologie

    Mönchengladbach, 41063, Germany

  • Klinikum Chemnitz gGmbH, Klinik für Innere Medizin III

    Chemnitz, 09116, Germany

  • Klinikum Oldenburg AöR, Universitätsklinik für Innere Medizin, Onkologie und Hämatologie

    Oldenburg, 26133, Germany

  • Klinikum Passau, II. Medizinische Klinik - Hämatologie, Onkologie und Palliativmedizin

    Passau, 94032, Germany

  • Klinikum rechts der Isar der TU München, Klinik und Poliklinik für Innere Medizin III

    München, 81675, Germany

  • RoMed Klinikum Rosenheim, Med. Klinik II / OTK

    Rosenheim, 83002, Germany

  • Robert-Bosch-Krankenhaus; Hämatologie, Onkologie und Palliativmedizin

    Stuttgart, 70376, Germany

  • Universitätsklinikum Ulm; Klinik für Innere Medizin Innere Medizin III

    Ulm, Baden-Wurttemberg, 89081, Germany

Conditions

Explore the condition pages connected to this study.