Immune therapy trial targets tough skin cancer before surgery

NCT ID NCT02775851

Ongoing Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study tests whether the immunotherapy drug pembrolizumab helps patients with desmoplastic melanoma, a rare type of skin cancer. It includes two groups: patients who can have surgery (to see if the drug shrinks tumors beforehand) and patients whose cancer cannot be surgically removed (to see if the drug controls it). The goal is to see if boosting the body's immune system can effectively fight this specific cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
AdventHealth Littleton

Littleton, Colorado, 80122, United States
AdventHealth Parker

Parker, Colorado, 80138, United States
AdventHealth Porter

Denver, Colorado, 80210, United States
Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States
Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122, United States
Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130, United States
Alegent Health Mercy Hospital

Council Bluffs, Iowa, 51503, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Banner North Colorado Medical Center

Greeley, Colorado, 80631, United States
Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539, United States
Bay Area Breast Surgeons Inc

Emeryville, California, 94608, United States
Bay Area Tumor Institute

Oakland, California, 94609, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Billings Clinic-Cody

Cody, Wyoming, 82414, United States
Boulder Community Foothills Hospital

Boulder, Colorado, 80303, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
CHI Health Good Samaritan

Kearney, Nebraska, 68847, United States
CHI Saint Vincent Cancer Center Hot Springs

Hot Springs, Arkansas, 71913, United States
Cambridge Medical Center

Cambridge, Minnesota, 55008, United States
Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004, United States
Cancer Center of Colorado at Sloan's Lake

Denver, Colorado, 80204, United States
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Centerpoint Medical Center LLC

Independence, Missouri, 64057, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Central Care Cancer Center - Garden City

Garden City, Kansas, 67846, United States
Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530, United States
Chancellor Center for Oncology

Newburgh, Indiana, 47630, United States
Cheyenne Regional Medical Center-West

Cheyenne, Wyoming, 82001, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
City of Hope South Pasadena

South Pasadena, California, 91030, United States
City of Hope Upland

Upland, California, 91786, United States
Coffeyville Regional Medical Center

Coffeyville, Kansas, 67337, United States
Colorado Blood Cancer Institute

Denver, Colorado, 80218, United States
Columbus Oncology and Hematology Associates Inc

Columbus, Ohio, 43214, United States
CommonSpirit Cancer Center Mercy

Durango, Colorado, 81301, United States
Commonwealth Cancer Center-Corbin

Corbin, Kentucky, 40701, United States
Community Hospital of Anaconda

Anaconda, Montana, 59711, United States
Community Medical Center

Missoula, Montana, 59804, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Cox Cancer Center Branson

Branson, Missouri, 65616, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Creighton University Medical Center

Omaha, Nebraska, 68131, United States
Deaconess Clinic Downtown

Evansville, Indiana, 47713, United States
Delaware Health Center-Grady Cancer Center

Delaware, Ohio, 43015, United States
Delaware Radiation Oncology

Delaware, Ohio, 43015, United States
Doctors Hospital

Columbus, Ohio, 43228, United States
Dublin Methodist Hospital

Dublin, Ohio, 43016, United States
Epic Care Cyberknife Center

Walnut Creek, California, 94597, United States
Epic Care Partners in Cancer Care

Emeryville, California, 94608, United States
Epic Care-Dublin

Dublin, California, 94568, United States
Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Fairview Clinics and Surgery Center Maple Grove

Maple Grove, Minnesota, 55369, United States
Fairview Lakes Medical Center

Wyoming, Minnesota, 55092, United States
Fairview Northland Medical Center

Princeton, Minnesota, 55371, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Farmington Health Center

Farmington, Utah, 84025, United States
Flaget Memorial Hospital

Bardstown, Kentucky, 40004, United States
Franciscan Research Center-Northwest Medical Plaza

Tacoma, Washington, 98405, United States
Freeman Health System

Joplin, Missouri, 64804, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
Good Samaritan Hospital - Cancer Centers of Colorado

Lafayette, Colorado, 80026, United States
Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Grand Valley Oncology

Grand Junction, Colorado, 81505, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greater Regional Medical Center

Creston, Iowa, 50801, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
HaysMed

Hays, Kansas, 67601, United States
Health Partners Inc

Minneapolis, Minnesota, 55454, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Health Center - Shelby Township

Shelby, Michigan, 48315, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford Medical Center-Columbus

Novi, Michigan, 48377, United States
Henry Ford Medical Center-Fairlane

Dearborn, Michigan, 48126, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Highline Medical Center-Main Campus

Burien, Washington, 98166, United States
Holy Cross Hospital

Fort Lauderdale, Florida, 33308, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Jefferson Healthcare

Port Townsend, Washington, 98368, United States
Jewish Hospital

Louisville, Kentucky, 40202, United States
Jewish Hospital Medical Center South

Shepherdsville, Kentucky, 40165, United States
Kansas Institute of Medicine Cancer and Blood Center

Lenexa, Kansas, 66219, United States
Keck Medical Center of USC Pasadena

Pasadena, California, 91105, United States
Knox Community Hospital

Mount Vernon, Ohio, 43050, United States
Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854, United States
Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864, United States
Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
Longmont United Hospital

Longmont, Colorado, 80501, United States
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Low Country Cancer Care

Savannah, Georgia, 31404, United States
Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Mary Bridge Children's Hospital and Health Center

Tacoma, Washington, 98405, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
Menorah Medical Center

Overland Park, Kansas, 66209, United States
Mercy Cancer Center-West Lakes

Clive, Iowa, 50325, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
Mercy Health - Perrysburg Hospital

Perrysburg, Ohio, 43551, United States
Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623, United States
Mercy Health - Saint Vincent Hospital

Toledo, Ohio, 43608, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin

Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Pittsburg

Pittsburg, Kansas, 66762, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Hospital Washington

Washington, Missouri, 63090, United States
Mercy Infusion Center - Chippewa

St Louis, Missouri, 63109, United States
Mercy Medical Center

Durango, Colorado, 81301, United States
Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314, United States
Mercy Medical Center-West Lakes

West Des Moines, Iowa, 50266, United States
Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011, United States
Midlands Community Hospital

Papillion, Nebraska, 68046, United States
Minimally Invasive Surgery Hospital

Lenexa, Kansas, 66219, United States
Minnesota Oncology - Burnsville

Burnsville, Minnesota, 55337, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420, United States
Mission Hope Medical Oncology - Santa Maria

Santa Maria, California, 93444, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Moffitt Cancer Center - McKinley Campus

Tampa, Florida, 33612, United States
Moffitt Cancer Center-International Plaza

Tampa, Florida, 33607, United States
Monroe Cancer Center

Monroe, Michigan, 48162, United States
Monticello Cancer Center

Monticello, Minnesota, 55362, United States
Mount Carmel East Hospital

Columbus, Ohio, 43213, United States
Mount Carmel Grove City Hospital

Grove City, Ohio, 43123, United States
Mount Carmel Health Center West

Columbus, Ohio, 43222, United States
Mount Sinai Comprehensive Cancer Center at Aventura

Aventura, Florida, 33180, United States
Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
Mountain Blue Cancer Care Center - Swedish

Englewood, Colorado, 80113, United States
MultiCare Auburn Medical Center

Auburn, Washington, 98001, United States
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

Spokane, Washington, 99204, United States
MultiCare Deaconess Cancer and Blood Specialty Center - North

Spokane, Washington, 99218, United States
MultiCare Deaconess Cancer and Blood Specialty Center - Valley

Spokane Valley, Washington, 99216, United States
MultiCare Gig Harbor Medical Park

Gig Harbor, Washington, 98335, United States
MultiCare Good Samaritan Hospital

Puyallup, Washington, 98372, United States
MultiCare Tacoma General Hospital

Tacoma, Washington, 98405, United States
National Jewish Health-Main Campus

Denver, Colorado, 80206, United States
National Jewish Health-Northern Hematology Oncology

Thornton, Colorado, 80260, United States
National Jewish Health-Western Hematology Oncology

Golden, Colorado, 80401, United States
Nebraska Cancer Specialists/Oncology Hematology West PC

Grand Island, Nebraska, 68803, United States
New Ulm Medical Center

New Ulm, Minnesota, 56073, United States
Newark Radiation Oncology

Newark, Ohio, 43055, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
Northwest Medical Specialties PLLC

Tacoma, Washington, 98405, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Anthony's Health Center

Alton, Illinois, 62002, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
OhioHealth Mansfield Hospital

Mansfield, Ohio, 44903, United States
OhioHealth Marion General Hospital

Marion, Ohio, 43302, United States
Onslow Memorial Hospital

Jacksonville, North Carolina, 28546, United States
Pacific Central Coast Health Center-San Luis Obispo

San Luis Obispo, California, 93401, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

Toledo, Ohio, 43606, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Research Medical Center

Kansas City, Missouri, 64132, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Riverton Hospital

Riverton, Utah, 84065, United States
Rocky Mountain Cancer Centers - Centennial

Centennial, Colorado, 80112, United States
Rocky Mountain Cancer Centers-Aurora

Aurora, Colorado, 80012, United States
Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States
Rocky Mountain Cancer Centers-Littleton

Littleton, Colorado, 80120, United States
Rocky Mountain Cancer Centers-Longmont

Longmont, Colorado, 80501, United States
Rocky Mountain Cancer Centers-Midtown

Denver, Colorado, 80218, United States
Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907, United States
Rocky Mountain Cancer Centers-Rose

Denver, Colorado, 80220, United States
Rocky Mountain Cancer Centers-Sky Ridge

Lone Tree, Colorado, 80124, United States
Rose Medical Center

Denver, Colorado, 80220, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
Saint Alphonsus Cancer Care Center-Baker City

Baker City, Oregon, 97814, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605, United States
Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687, United States
Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Anthony Hospital

Lakewood, Colorado, 80228, United States
Saint Clare Hospital

Lakewood, Washington, 98499, United States
Saint Elizabeth Hospital

Enumclaw, Washington, 98022, United States
Saint Elizabeth Regional Medical Center

Lincoln, Nebraska, 68510, United States
Saint Francis Hospital

Federal Way, Washington, 98003, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint George Regional Medical Center

St. George, Utah, 84770, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Hospital - Cancer Centers of Colorado

Denver, Colorado, 80218, United States
Saint Joseph Hospital East

Lexington, Kentucky, 40509, United States
Saint Joseph London

London, Kentucky, 40741, United States
Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504, United States
Saint Joseph Regional Cancer Center

Bryan, Texas, 77802, United States
Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States
Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, 81501, United States
Saint Michael Cancer Center

Silverdale, Washington, 98383, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Rita's Medical Center

Lima, Ohio, 45801, United States
Saint Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Saints Mary and Elizabeth Hospital

Louisville, Kentucky, 40215, United States
Salina Regional Health Center

Salina, Kansas, 67401, United States
Sandra L Maxwell Cancer Center

Cedar City, Utah, 84720, United States
Singing River Hospital

Pascagoula, Mississippi, 39581, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
South Jordan Health Center

South Jordan, Utah, 84009, United States
Southeastern Medical Oncology Center-Clinton

Clinton, North Carolina, 28328, United States
Southeastern Medical Oncology Center-Goldsboro

Goldsboro, North Carolina, 27534, United States
Southeastern Medical Oncology Center-Jacksonville

Jacksonville, North Carolina, 28546, United States
Southern Ohio Medical Center

Portsmouth, Ohio, 45662, United States
Strecker Cancer Center-Belpre

Belpre, Ohio, 45714, United States
Summit Cancer Care-Candler

Savannah, Georgia, 31405, United States
Swedish Medical Center

Englewood, Colorado, 80113, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States
The Medical Center of Aurora

Aurora, Colorado, 80012, United States
The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061, United States
The University of Kansas Cancer Center-South

Kansas City, Missouri, 64131, United States
The Women's Imaging Center

Denver, Colorado, 80209, United States
TriHealth Cancer Institute-Anderson

Cincinnati, Ohio, 45255, United States
TriHealth Cancer Institute-Westside

Cincinnati, Ohio, 45247, United States
UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, 90095, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
USC Norris Oncology/Hematology-Newport Beach

Newport Beach, California, 92663, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University Health Truman Medical Center

Kansas City, Missouri, 64108, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center - Lee's Summit

Lee's Summit, Missouri, 64064, United States
University of Kansas Cancer Center - North

Kansas City, Missouri, 64154, United States
University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210, United States
University of Kansas Cancer Center-West

Kansas City, Kansas, 66112, United States
University of Kansas Clinical Research Center

Fairway, Kansas, 66205, United States
University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606, United States
University of Kansas Hospital-Westwood Cancer Center

Westwood, Kansas, 66205, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
UofL Health Medical Center Northeast

Louisville, Kentucky, 40245, United States
Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Walter Knox Memorial Hospital

Emmett, Idaho, 83617, United States
Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Western Surgical Care

Denver, Colorado, 80220, United States

Conditions

Explore the condition pages connected to this study.

DESMOPLASTIC MELANOMA