New combo therapy shows promise for young cancer patients who relapsed

NCT ID NCT03445858

First seen Jan 25, 2026 · Last updated May 12, 2026 · Updated 13 times

Summary

This early-phase study tested a combination of three treatments—pembrolizumab, decitabine, and targeted radiation—in 22 children and young adults (ages 1 to 40) with relapsed or refractory solid tumors or lymphoma. The main goals were to see if the combination is safe and tolerable, and to get an early look at whether it can shrink tumors. The study is complete, but results are not yet reported.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.