New drug cocktail shows promise against deadly thyroid cancer before surgery
NCT ID NCT04675710
First seen Oct 31, 2025 · Last updated Apr 23, 2026 · Updated 26 times
Summary
This study tests whether giving three drugs (pembrolizumab, dabrafenib, and trametinib) before surgery can help doctors more completely remove a rare and fast-growing thyroid cancer called anaplastic thyroid cancer. The trial includes 30 adults whose cancer has a specific BRAF gene mutation. The goal is to see if this approach improves survival and allows for full tumor removal.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic Taussig Cancer Institute
Cleveland, Ohio, 44195, United States
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Huntsman Cancer Institute at the University of Utah
Salt Lake City, Utah, 84112, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Mayo Clinic
Rochester, Minnesota, 55901, United States
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Stanford School of Medicine
Stanford, California, 94304, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
Conditions
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