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New hope for brain cancer: immunotherapy plus chemo tested in small trial

NCT ID NCT06475235

Recruiting now Disease control Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jan 10, 2026 · Last updated May 08, 2026 · Updated 15 times

Summary

This early-phase study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy is safe and effective for people newly diagnosed with primary central nervous system lymphoma, a rare brain cancer. About 15 participants will receive the combination and be monitored for side effects and tumor response. The goal is to find a better treatment option for this hard-to-treat disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

LYMPHOMA PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA