Immunotherapy and radiation combo tested for rare chest cancer

NCT ID NCT04166734

First seen Feb 04, 2026 · Last updated May 13, 2026 · Updated 12 times

Summary

This early-stage trial tested whether combining the immunotherapy drug pembrolizumab with precise, high-dose radiation (SBRT) could help people with advanced malignant pleural mesothelioma, a rare cancer of the lung lining. The study aimed to check safety and side effects in patients whose cancer had worsened after standard chemotherapy. Only 5 people took part before the study was stopped early.

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Contacts and locations

Locations

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Royal Marsden NHS Foundation Trust

    Chelsea, United Kingdom

Conditions

Explore the condition pages connected to this study.