New drug combo shows promise for tough ovarian cancer

NCT ID NCT05296512

First seen Dec 18, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This study tests whether combining two drugs, pembrolizumab and lenvatinib, can shrink tumors or slow cancer growth in people with recurrent clear cell ovarian cancer. About 30 participants who have already tried at least one other treatment will receive the drug combination. The main goals are to see how many respond and how long the cancer stays under control.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Mayo Clinic Comprehensive Cancer Center

    Rochester, Minnesota, 55905, United States

  • University of Chicago Medicine

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.