New drug targets hard-to-treat neuroendocrine cancers in early trial
NCT ID NCT05652686
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 27 times
Summary
This study tests a new drug, peluntamig, in people with advanced neuroendocrine cancers (like small cell lung cancer) that have a specific marker called DLL3. The trial has two parts: first finding the safest dose, then testing it alone or with chemotherapy. About 203 participants will join to see if the drug is safe and works against these cancers.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope (City of Hope National Medical Center, City of Hope Medical Center)
RECRUITINGDuarte, California, 91010, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Mays Cancer Center / University of Texas, San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
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Sarah Cannon Research Institute University of Oklahoma
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Sarah Cannon Research Institute at HealthONE
RECRUITINGDenver, Colorado, 80218, United States
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Sidney Kimmel Comprehensive Cancer Center at John Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
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The University of Texas, MD Anderson Cancer Center
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
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Washington University School of Medicine (Siteman Cancer Center)
RECRUITINGSt Louis, Missouri, 63108, United States
Conditions
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