Can a new dressing make skin graft donor sites less painful?

NCT ID NCT07734519

First seen Jul 29, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This trial tests whether a new dressing called Pelashield reduces pain and improves scar appearance compared to the standard Xeroform dressing at skin graft donor sites. Each participant will have their donor site split in half, with one half receiving Pelashield and the other Xeroform, allowing direct comparison. The study enrolls adults undergoing split-thickness skin grafts and measures pain scores and scar quality over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pelashield dressing (a new skin graft donor-site dressing) compared to Xeroform dressing
What this could lead to
If Pelashield reduces pain or improves scar appearance, it could become a better option for people undergoing skin grafts.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The new dressing might not be better than the standard one.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States

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