Experimental combo aims to boost immune attack on tough cancers

NCT ID NCT07438093

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a combination of two drugs—peginterferon alfa-2b and an anti-PD-1 antibody—in about 60 people with advanced or metastatic solid tumors who have no standard treatment options left. The main goal is to find a safe dose and check for side effects. Researchers will also look for early signs that the combo might shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

peginterferon alfa-2b combined with an anti-PD-1 antibody

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumors who have run out of standard therapies.

What could go wrong

This is a very early, small Phase 1 trial focused on safety and dosing, not yet on effectiveness. The combination may cause significant side effects and may not shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••