New drug combo shows promise for tough leukemia cases

NCT ID NCT04666649

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This early-stage trial tested a combination of two drugs, pegcrisantaspase and venetoclax, in 27 adults whose acute myeloid leukemia had returned or not responded to prior treatments. The main goals were to check safety and find the best dose. Researchers also looked at how many patients achieved complete remission. This is not a cure, but aims to control the disease.

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Contacts and locations

Locations

  • Greenebaum Cancer Center at University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

Conditions

Explore the condition pages connected to this study.