New study hopes to spot sepsis in kids faster with MicroRNA

NCT ID NCT02055105

Recruiting now Knowledge-focused Sponsor: Phoenix Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether measuring tiny molecules called microRNA in the blood can help doctors detect sepsis in children more quickly and accurately than current methods. Researchers will follow 50 children admitted to the pediatric ICU with suspected sepsis, tracking their microRNA levels and comparing them to standard severity scores. The goal is to see if these biomarkers can predict the risk of death or organ failure better than existing tools.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a faster, more accurate way to diagnose sepsis in children and predict who is at highest risk.
What could go wrong: This is a small, early-stage observational study. It only measures biomarkers and does not test a treatment, so it may not directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Systemic Inflammatory Response Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC INFLAMMATORY RESPONSE SYNDROME

Contacts and locations

Locations

Phoenix Children's Hospital
RECRUITING

Phoenix, Arizona, 85016, United States
Phoenix Children's Hospital
RECRUITING

Phoenix, Arizona, 85019, United States

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