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Battle of the scopes: which surgery best clears children's kidney stones?

NCT ID NCT07700251

Disease control Sponsor: South Valley University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial compares two keyhole surgeries — retrograde intrarenal surgery (RIRS) and mini-percutaneous nephrolithotomy (mini-PCNL) — for removing kidney stones up to 2 cm in children aged 1 to 18. The goal is to see which method clears more stones with fewer complications. Both procedures are already used in adults, but their relative safety and effectiveness in children are not well established.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
two surgical procedures: retrograde intrarenal surgery (RIRS) and mini-percutaneous nephrolithotomy (mini-PCNL)
What this could lead to
If one procedure proves clearly safer and more effective, it could become the preferred standard for treating small-to-medium kidney stones in children.
What could go wrong
This is a single-center trial with only 60 children, so results may not apply broadly. Both procedures carry risks like bleeding, infection, or incomplete stone removal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 year to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged 1 to 18 years . * Presence of a renal stone ≤2 cm in maximum diameter (single or multiple). * Stone located in the renal pelvis and/or calyces. * Normal renal function (based on age-adjusted serum creatinine and/or eGFR). * No prior surgical intervention for the current stone episode. Exclusion Criteria: * Anatomical abnormalities of the urinary tract (e.g., ureteropelvic junction obstruction, horseshoe kidney). * Bleeding disorders or uncorrected coagulopathy. * Active urinary tract infection at the time of surgery. * Patients with contraindications to general anesthesia.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pediatric renal stone

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • South Valley University Hospital

    RECRUITING

    Qina, South Valley, Egypt