New hope for kids with tough cancers: experimental drug cocktails tested
NCT ID NCT04238819
Summary
This study tested whether adding a drug called abemaciclib to standard chemotherapy is safe and effective for children and young adults whose solid tumors returned or didn't respond to other treatments. It involved 47 participants with various cancers, including neuroblastoma, and tested different drug combinations to find the best doses. The main goal was to see if these combinations could help control the cancer.
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Contacts and locations
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Locations
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Atrium Health - Carolinas Medical Center
Charlotte, North Carolina, 28203, United States
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Centre Leon Berard
Lyon, Rhône, 69373 CEDEX 08, France
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Charité Campus Virchow-Klinikum
Berlin, 13353, Germany
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Children's Hospital of Philadelphia (CHOP)
Philadelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Cohen Children's Medical Center
New Hyde Park, New York, 11040, United States
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Fondazione Policlinico Universitario Agostino Gemelli
Rome, Lazio, 168, Italy
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Gustave Roussy
Villejuif, Val-de-Marne, 94800, France
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Hospital Infantil Universitario Niño Jesús
Madrid, Madrid, Comunidad de, 28009, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, Barcelona [Barcelona], 8035, Spain
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Hospital Universitari i Politecnic La Fe
Valencia, 46026, Spain
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Institut Curie
Paris, 75248, France
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Kaiser Permanente Oakland
Oakland, California, 94611, United States
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Kaiser Permanente Roseville
Roseville, California, 95661, United States
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Kaiser Permanente Santa Clara
Santa Clara, California, 95051, United States
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Lifespan Cancer Institute
Providence, Rhode Island, 02906, United States
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National Cancer Center Hospital
Chuo Ku, Tokyo, 104-0045, Japan
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Perth Children's Hospital
Perth, Western Australia, 6009, Australia
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, 46202, United States
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Spectrum Health
Grand Rapids, Michigan, 49503, United States
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The Regents of the University of California - Los Angeles (UCLA Pediatrics)
Los Angeles, California, 90095-1752, United States
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UZ Gent
Ghent, Oost-Vlaanderen, 9000, Belgium
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Universitaetsklinikum Essen
Essen, North Rhine-Westphalia, 45122, Germany
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Universitaetsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, 69120, Germany
Conditions
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