New hope for kids with deadly brain and nerve cancers: personalized cell therapy trial launches

NCT ID NCT04837547

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 28 times

Summary

This early-phase study tests a new approach for children with recurrent neuroblastoma or newly diagnosed DIPG, two aggressive cancers with few options. The treatment combines drugs tailored to the child's tumor with a personalized cell therapy using their own immune cells and stem cells. The main goal is to see if this combination is safe and tolerable for up to 24 children.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Levine Children's Hospital

    Charlotte, North Carolina, 28204, United States

  • Penn State Milton S. Hershey Medical Center and Children's Hospital

    Hershey, Pennsylvania, 17033, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

Conditions

Explore the condition pages connected to this study.