New hope for kids with deadly brain and nerve cancers: personalized cell therapy tested

NCT ID NCT04837547

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 36 times

Summary

This early-stage trial tests a personalized treatment for children with recurrent neuroblastoma or a newly diagnosed brainstem tumor called DIPG. The approach combines targeted drugs with the child's own immune cells and stem cells, all customized to their tumor. The main goal is to check safety and find the right dose, not yet to prove it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Levine Children's Hospital

    Charlotte, North Carolina, 28204, United States

  • Penn State Milton S. Hershey Medical Center and Children's Hospital

    Hershey, Pennsylvania, 17033, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

Conditions

Explore the condition pages connected to this study.