New combo therapy shows promise in breast cancer biomarker study

NCT ID NCT02999477

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tested a combination of chemotherapy (nab-paclitaxel) and immunotherapy (pembrolizumab) in 32 people with hormone receptor-positive breast cancer. The goal was to see how the treatment changed a biomarker called PD-L1 in tumor tissue. Results help researchers understand how the immune system responds to this treatment approach.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.