Blood product showdown: which stops bleeding faster in heart surgery?

NCT ID NCT06144125

Recruiting now Disease control Sponsor: Konkuk University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares two blood products—prothrombin complex concentrate (PCC) and fresh frozen plasma (FFP)—for controlling bleeding in people undergoing heart valve surgery. Doctors use a special test to guide which product to give and measure how quickly bleeding stops. The goal is to see which approach leads to faster bleeding control and less need for additional blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: prothrombin complex concentrate and fresh frozen plasma
What this could lead to: If one product works faster or better, it could improve bleeding control and reduce transfusions during heart surgery.
What could go wrong: This is a single-center trial with 100 participants, so results may not apply broadly. Both products carry risks like clotting or allergic reactions.

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Conditions

The condition(s) this trial relates to.

heart valve disorder hemophilia B Hemorrhage thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC VALVE DISEASE

Contacts and locations

Locations

Konkuk University Medical Center
RECRUITING

Seoul, Seoul, 05030, South Korea

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