Could a daily pill stop HHT nosebleeds? new trial investigates.
NCT ID NCT03850964
First seen Mar 26, 2026 · Last updated May 13, 2026 · Updated 7 times
Summary
This study tests whether a low dose of the drug pazopanib, taken daily for 24 weeks, can reduce the severity and duration of nosebleeds in people with hereditary hemorrhagic telangiectasia (HHT). About 70 participants will receive either the active drug or a placebo. The researchers will also check if the drug improves anemia (low red blood cells) caused by blood loss. The goal is to manage symptoms, not cure the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Augusta University
Augusta, Georgia, 30912, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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John Hopkins University
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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University of California - Los Angeles
Los Angeles, California, 90095, United States
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University of Colorado
Denver, Colorado, 80045, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Texas - Southwestern
Dallas, Texas, 75390, United States
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University of Utah Medical Center
Salt Lake City, Utah, 84132, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.