New hope for controlling debilitating nosebleeds in rare disease
NCT ID NCT03850964
Summary
This study is testing whether a drug called pazopanib can help people with hereditary hemorrhagic telangiectasia (HHT), a genetic disorder that causes frequent, severe nosebleeds and anemia. About 70 participants will take either pazopanib or a placebo pill daily for 24 weeks to see if it reduces nosebleed duration and improves blood counts. The goal is to better control the disease's symptoms and reduce the need for blood transfusions.
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Contacts and locations
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Locations
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Augusta University
Augusta, Georgia, 30912, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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John Hopkins University
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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University of California - Los Angeles
Los Angeles, California, 90095, United States
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University of Colorado
Denver, Colorado, 80045, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Texas - Southwestern
Dallas, Texas, 75390, United States
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University of Utah Medical Center
Salt Lake City, Utah, 84132, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.