New immune therapy aims to extend life in Hard-to-Treat prostate cancer

NCT ID NCT07164443

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 25 times

Summary

This study tests a new drug called pasritamig, which helps the body's immune cells attack prostate cancer cells. It is for people with advanced prostate cancer that has spread and no longer responds to hormone therapy. About 663 participants will receive either pasritamig plus best supportive care or a placebo plus best supportive care. The main goal is to see if the drug helps people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Maria Middelares
RECRUITING

Ghent, 9000, Belgium
AZ Sint-Jan
RECRUITING

Bruges, 8000, Belgium
Arthur J E Child Comprehensive Cancer Centre
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Associacao Hospitalar Moinhos de Vento
RECRUITING

Porto Alegre, 90035 901, Brazil
Az Groeninge
RECRUITING

Kortrijk, 8500, Belgium
Azienda Di Rilievo Nazionale E Di Alta Specializzazione
RECRUITING

Palermo, 90127, Italy
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, 80131, Italy
BC Cancer Vancouver
RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Bay Pines VA Healthcare System
RECRUITING

Bay Pines, Florida, 33744, United States
Blue Ridge Cancer Care
RECRUITING

Roanoke, Virginia, 24014, United States
CHC MontLegia
RECRUITING

Liège, 4000, Belgium
CHRU Brest - Hopital Morvan
RECRUITING

Brest, 29200, France
CHU Lyon Sud
RECRUITING

Pierre-Bénite, 69495, France
CHU de Quebec Universite Laval
RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Canisius-Wilhelmina ZH
RECRUITING

Nijmegen, 6532 SZ, Netherlands
Carolina Urologic Research Center
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
Centre Georges Francois Leclerc
RECRUITING

Dijon, 21000, France
Centre Leon Berard
RECRUITING

Lyon, 69008, France
Centre Oscar Lambret
RECRUITING

Lille, 59000, France
Centro de Pesquisa e Ensino em Oncologia de Santa Catarina CEPEN
RECRUITING

Florianópolis, 88034 000, Brazil
Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 833, Taiwan
Chongqing University Cancer Hospital
RECRUITING

Chongqing, 400030, China
Chonnam National University Hwasun Hospital
RECRUITING

Hwasungun, 58128, South Korea
Chu Helora Hospital La Louviere Site Jolimont
RECRUITING

La Louvière, 7100, Belgium
Chungnam National University Hospital
RECRUITING

Daejeon, 35015, South Korea
Clinique Saint Pierre
RECRUITING

Ottignies, 1340, Belgium
Cliniques Universitaires Saint Luc
RECRUITING

Brussels, 1200, Belgium
Colorado Clinical Research
RECRUITING

Lakewood, Colorado, 80228, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Compass Oncology
RECRUITING

Portland, Oregon, 97227, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02115, United States
East Jefferson General Hospital
RECRUITING

Metairie, Louisiana, 70006, United States
Erasmus MC
RECRUITING

Rotterdam, 3015 GD, Netherlands
Fiona Stanley Hospital
RECRUITING

Murdoch, 6150, Australia
Florida Cancer Specialists & Research Institute
RECRUITING

Fort Myers, Florida, 33901, United States
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
Fondazione Policlinico Universitario A Gemelli IRCCS
RECRUITING

Roma, 00168, Italy
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109, United States
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China
Fundacao Antonio Prudente A C Camargo Cancer Center
RECRUITING

São Paulo, 01509 900, Brazil
Ghent University Hospital
RECRUITING

Ghent, 9000, Belgium
Gibbs Cancer Center
RECRUITING

Spartanburg, South Carolina, 29303, United States
Gibbs Cancer Center and Research Institute Pelham
RECRUITING

Greer, South Carolina, 29650, United States
Gustave Roussy
RECRUITING

Villejuif, 94800, France
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States
Henry Ford Cancer Detroit
RECRUITING

Detroit, Michigan, 48202, United States
Hopital Saint Joseph
RECRUITING

Paris, 75014, France
Hopitaux universitaires de Strasbourg
RECRUITING

Strasbourg, 672098, France
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 08035, Spain
Hosp Virgen de La Victoria
RECRUITING

Málaga, 29010, Spain
Hosp. Univ. 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hosp. Univ. Ramon Y Cajal
RECRUITING

Madrid, 28034, Spain
Hosp. de Jerez de La Frontera
RECRUITING

Jerez de la Frontera, 11407, Spain
I.C.O. Rene Gauducheau
RECRUITING

Saint-Herblain, 44805, France
ICON Cancer Care
RECRUITING

Kurralta Park, 5037, Australia
IN VIVO Sp. z o.o
RECRUITING

Bydgoszcz, 85 048, Poland
IOV IRCCS Padova
RECRUITING

Padova, 35128, Italy
Institut Bergonie
RECRUITING

Bordeaux, 33000, France
Institut de Cancerologie de Lorraine
RECRUITING

Vandœuvre-lès-Nancy, 54519, France
Institute of Science Tokyo Hospital
RECRUITING

Bunkyō City, 113 8519, Japan
Instituto Joinvilense de Hematologia e Oncologia Ltda Centro de Hematologia e Oncologia
RECRUITING

Joinville, 89201 260, Brazil
Isala Kliniek
RECRUITING

Zwolle, 8025 AB, Netherlands
Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy
Johns Hopkins Office of Capital Region Research - Sibley Memorial Hospital
RECRUITING

Washington D.C., District of Columbia, 20016, United States
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21287, United States
Kanazawa University Hospital
RECRUITING

Kanazawa, 920 8641, Japan
Keystone Urology Specialists
RECRUITING

Lancaster, Pennsylvania, 17601, United States
Klinikum Nuernberg Nord
RECRUITING

Nuremberg, 90419, Germany
Klinikum rechts der Isar der TU Muenchen
RECRUITING

München, 81675, Germany
Kobe University Hospital
RECRUITING

Kobe, 650 0017, Japan
Krankenhaus NorthWest
RECRUITING

Frankfurt am Main, 60488, Germany
Kyushu University Hospital
RECRUITING

Fukuoka, 812 8582, Japan
Lakeridge Health
RECRUITING

Oshawa, Ontario, L1G2B9, Canada
Liga Norte Riograndense Contra O Cancer
RECRUITING

Natal, 59062 000, Brazil
Linkou Chang Gung Memorial Hospital
RECRUITING

Taoyuan, 333, Taiwan
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Maastricht UMC
RECRUITING

Maastricht, 6229 HX, Netherlands
Martini Ziekenhuis
RECRUITING

Groningen, 9728NT, Netherlands
Martini-Klinik am UKE GmbH
RECRUITING

Hamburg, 20246, Germany
Michael E DeBakey VA Medical Center
RECRUITING

Houston, Texas, 77030, United States
MidLantic Urology
RECRUITING

Bala-Cynwyd, Pennsylvania, 19004, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
NYU Langone Health Laura and Isaac Perlmutter Cancer Center
RECRUITING

New York, New York, 10016, United States
NYU Langone Hospital Long Island
RECRUITING

Mineola, New York, 11501, United States
NYU Langone Hospitals
RECRUITING

Brooklyn, New York, 11220, United States
Nanjing Drum Tower Hospital
RECRUITING

Nanjing, 210008, China
Nantong Tumor Hospital
RECRUITING

Nantong, 226300, China
Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy
RECRUITING

Warsaw, 02 781, Poland
National Cancer Center
RECRUITING

Goyang-si, 10408, South Korea
National Hospital Organization Shikoku Cancer Center
RECRUITING

Matsuyama, 791-0280, Japan
National Hospital Organization Tokyo Medical Center
RECRUITING

Meguro Ku, 152 8902, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan
Oregon Urology Institute
RECRUITING

Springfield, Oregon, 97477, United States
Ospedali Riuniti Foggia
RECRUITING

Foggia, 71122, Italy
Pan American Center for Oncology Trials LLC
RECRUITING

Rio Piedras, 00935, Puerto Rico
Peking University First Hospital
RECRUITING

Beijing, 100034, China
Penn Medicine Abramson Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Peter MacCallum Cancer Centre
RECRUITING

Melbourne, 3000, Australia
Princess Alexandra Hospital
RECRUITING

Woolloongabba, 4102, Australia
Princess Margaret Hospital
RECRUITING

Toronto, Ontario, M5G 2C1, Canada
Puerto Rico Medical Research Center
RECRUITING

San Juan, 00917, Puerto Rico
Ralph H Johnson Veterans Hospital
RECRUITING

Charleston, South Carolina, 29401, United States
Reinier de Graaf Gasthuis
RECRUITING

Delft, 2625 AD, Netherlands
Rocky Mountain Cancer Centers
RECRUITING

Aurora, Colorado, 80012, United States
Ronald Reagan UCLA Medical Center
RECRUITING

Los Angeles, California, 90095, United States
Royal Marsden Hospital (Sutton)
RECRUITING

Sutton, SM2 5PT, United Kingdom
Saitama Medical University International Medical Center
RECRUITING

Hidaka, 350 1298, Japan
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Spaarne Gasthuis
RECRUITING

Hoofddorp, 2134 TM, Netherlands
Staedtisches Klinikum Braunschweig
RECRUITING

Braunschweig, 38126 DE, Germany
Studienpraxis Urologie Nurtingen
RECRUITING

Nürtingen, 72622, Germany
Sun Yat Sen University Cancer Center
RECRUITING

Guangzhou, 510060, China
Sunnybrook Health Sciences Center
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Szpital Grochowski Im Dr Med Rafala Masztaka Sp Z O O
RECRUITING

Warsaw, 04 073, Poland
Szpital Wojewodzki im Mikolaja Kopernika w Koszalinie
RECRUITING

Koszalin, 75 581, Poland
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 112, Taiwan
Tennessee Oncology - Chattanooga
RECRUITING

Chattanooga, Tennessee, 37404, United States
Tennessee Oncology Nashville
RECRUITING

Nashville, Tennessee, 37203, United States
Tergooi
RECRUITING

Hilversum, 1212 VG, Netherlands
Texas Oncology West Texas
RECRUITING

Wichita Falls, Texas, 76310, United States
The Catholic University of Korea Seoul St Marys Hospital
RECRUITING

Seoul, 06591, South Korea
The Christie NHS Foundation Trust Christie Hospital
RECRUITING

Manchester, M20 4BX, United Kingdom
The First Affiliated Hospital of Guangxi Medical University
RECRUITING

Nanning, 530021, China
The First Affiliated Hospital of Ningbo University
RECRUITING

Ningbo, 315010, China
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, 325000, China
The First Affiliated Hospital of Xian Jiaotong University
RECRUITING

Xi'an, 710061, China
The First Bethune Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Second Hospital Of Tianjin Medical University
RECRUITING

Tianjin, 300211, China
Toho University Sakura Medical Center
RECRUITING

Sakura, 285-8741, Japan
Tungs' Taichung MetroHarbor Hospital
RECRUITING

Taichung, 435, Taiwan
UPMC Cancer Centers
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Universitaetsklinikum Duesseldorf
RECRUITING

Düsseldorf, 40225, Germany
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Heidelberg Nationales Centrum fuer Tumorerkrankungen
RECRUITING

Heidelberg, 69120, Germany
Universitaetsklinikum Muenster
RECRUITING

Münster, 48149, Germany
University College London Hospitals
RECRUITING

London, WC1E 6BT, United Kingdom
University Hospital of Cleveland
RECRUITING

Cleveland, Ohio, 44106, United States
University Hospitals Birmingham NHS Foundation Trust
RECRUITING

Birmingham, B15 2TH, United Kingdom
University Of Minnesota Medical Center
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of California at San Diego
RECRUITING

La Jolla, California, 92093, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States
University of Michigan Health System
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Washington
RECRUITING

Seattle, Washington, 98195, United States
Uniwersytecki Szpital Kliniczny w Bialymstoku
RECRUITING

Bialystok, 15 276, Poland
Urologicum Duisburg
RECRUITING

Duisburg, 47169, Germany
Urology Clinics of North Texas
RECRUITING

Dallas, Texas, 75231, United States
Utah Cancer Specialists
RECRUITING

Salt Lake City, Utah, 84106, United States
VA Puget Sound Healthcare System
RECRUITING

Seattle, Washington, 98108, United States
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States
Warringal Private Hospital
RECRUITING

Heidelberg, 3084, Australia
West China Hospital of Sichuan University
RECRUITING

Chengdu, 610041, China
XCancer Omaha / Urology Cancer Center
RECRUITING

Omaha, Nebraska, 68130, United States
Yokohama City University Hospital
RECRUITING

Yokohama, 236 0004, Japan
Yokohama City University Medical Center
RECRUITING

Yokohama, 232 0024, Japan
Yokosuka Kyosai Hospital
RECRUITING

Yokosuka, 238 8558, Japan
ZAS Augustinus
RECRUITING

Wilrijk, 2610, Belgium
Zhongnan Hospital Wu Han University
RECRUITING

Wuhan, 430071, China

Conditions

Explore the condition pages connected to this study.

METASTATIC CASTRATION-RESISTANT PROSTATE NEOPLASMS