New hope for shaky hands: experimental drug targets stubborn Parkinson's tremor

NCT ID NCT05642442

Summary

This study tested whether a new drug called suvecaltamide could help reduce moderate to severe tremor in people with Parkinson's disease whose shaking is not adequately controlled by their current medications. Over 17 weeks, 169 participants were randomly assigned to receive either the study drug or a placebo to compare effects. The main goal was to see if the drug improved tremor severity and its impact on daily activities like eating and dressing.

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Contacts and locations

Locations

  • Albany Medical College

    Albany, New York, 12208, United States

  • Central Texas Neurology Consultants

    Round Rock, Texas, 78681, United States

  • Centrum Medyczne Plejady

    Krakow, 30-363, Poland

  • Clinical Neuroscience Solutions, Inc.

    Jacksonville, Florida, 32256, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Curiositas-ad-sanum Beratungs-und Studien GmbH

    Haag in Oberbayern, 83527, Germany

  • Dent Neurologic Institute

    Amherst, New York, 14226, United States

  • Deutsche Klinik fur Diagnostik Helios Klinik Wiesbaden

    Hessen, 65191, Germany

  • ETG Neuroscience Sp. z o.o.

    Warsaw, 02-777, Poland

  • EverGreenHealth Neuroscience Institute

    Kirkland, Washington, 98034, United States

  • Gabinety Lekarskie Rivermed Sp. z o.o.

    Poznan, 61-441, Poland

  • Hawaii Pacific Health

    Honolulu, Hawaii, 96817, United States

  • Hospital Ramón y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Cruces

    Barakaldo, 48903, Spain

  • Hospital Universitario Virgen Macarena

    Seville, 41009, Spain

  • Hospital Universitario de La Princesa

    Madrid, 28006, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041, Spain

  • Keck School of Medicine of University of Southern California (USC)

    Los Angeles, California, 90033, United States

  • Maxxmed Centrum Zdrowia i Urody w Lublinie

    Lublin, 20-080, Poland

  • Movement Disorders Center of Arizona

    Scottsdale, Arizona, 85258, United States

  • NeuroTrials Research Inc.

    Atlanta, Georgia, 30328, United States

  • Neurologia Slaska Centrum Medyczne

    Katowice, 40-689, Poland

  • Neurology of Central Florida Research Center LLC

    Altamonte Springs, Florida, 32714, United States

  • Niepubliczny Zaklad Opieki Zdrowotnej Neuromed M.i M. Nastaj Spólka Partnerska

    Lublin, 20-064, Poland

  • Northwestern Medical Group, Department of Neurology

    Chicago, Illinois, 60611, United States

  • Parkinson's Disease and Movement Disorder Center of Boca Raton

    Boca Raton, Florida, 33486, United States

  • Pharmakologisches Studienzentrum Chemnitz GmbH

    Chemnitz, 091111, Germany

  • South Shore Neurologic Associates PC

    Patchogue, New York, 11772, United States

  • The Nene and Jamie Koch Comprehensive Movement Disorders Center

    Albuquerque, New Mexico, 87106, United States

  • USF Parkinson's Disease and Movement Disorders Center

    Tampa, Florida, 33613, United States

  • University of Cincinnati Gardner Neuroscience Institute (UCGNI)

    Cincinnati, Ohio, 45219, United States

  • University of Colorado Hospital Anschutz Outpatient Pavilion

    Aurora, Colorado, 80045, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Kentucky, College of Medicine, Department of Neurology

    Lexington, Kentucky, 40536, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Velocity Clinical Research Germany GmbH, Location Wiesbaden

    Wiesbaden, 65189, Germany

  • Zentrum f. klinische Forschung Dr. I. Schöll

    Bad Homburg, 61350, Germany

Conditions

Explore the condition pages connected to this study.