New Parkinson's drug candidate enters early human safety trials

NCT ID NCT06565195

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 35 times

Summary

This early-stage study tests a new drug called LY3962681 for safety and how the body processes it. First, healthy volunteers get a single dose into their spinal fluid. Then, people with Parkinson's disease get two doses, spaced months apart. The goal is to see if the drug is safe and to measure its effects on Parkinson's-related proteins.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Austin Clinic PPD

    RECRUITING

    Austin, Texas, 78744-1625, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ehime University Hospital

    NOT_YET_RECRUITING

    Tōon, Ehime, 791-0295, Japan

  • Oita University Hospital

    NOT_YET_RECRUITING

    Yufu, Oita Prefecture, 879-5593, Japan

  • P-One Clinic, Keikokai Medical Corporation

    RECRUITING

    Hachiōji, Tokyo, 192-0071, Japan

Conditions

Explore the condition pages connected to this study.