New antibody therapy aims to put the brakes on Parkinson's

NCT ID NCT03100149

Summary

This study is testing whether an intravenous drug called prasinezumab can slow the progression of Parkinson's disease in people who are in the early stages. Over 300 participants will receive either the drug or a placebo for one year, with the option to continue treatment for up to 11 years. The main goal is to see if the drug can reduce the worsening of both movement and non-movement symptoms.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Associated Neurologists of Southern CT PC

    Fairfield, Connecticut, 06824, United States

  • Aventura Neurologic Associates

    Aventura, Florida, 33180, United States

  • Barrow Neurology Clinics

    Phoenix, Arizona, 85013, United States

  • Baylor College

    Houston, Texas, 77030, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • CHU Poitiers

    Poitiers, 86021, France

  • CHU Rouen Charles Nicolle

    Rouen, 76031, France

  • CHU de Nantes - Hopital Laennec

    Saint-Herblain, 44800, France

  • CHU de Nice Hopital Pasteur

    Nice, 06002, France

  • CIC - Hôpital Purpan

    Toulouse, 31059, France

  • CenExel Rocky Mountain Clinical Research, LLC

    Englewood, Colorado, 80113, United States

  • Central Texas Neurology Consultants

    Round Rock, Texas, 78681, United States

  • Clinica Universidad de Navarra

    Pamplona/iruña, Navarre, 31008, Spain

  • Columbia University

    New York, New York, 10032, United States

  • Corewell Health Neurology and Epilepsy - Beltline

    Grand Rapids, Michigan, 49525, United States

  • DZNE Clinical Trial Unit

    München, 81377, Germany

  • Fundacion Hospital de Alcorcon

    Alcorcón, Madrid, 28922, Spain

  • Groupe Hospitalier Pellegrin

    Bordeaux, 33000, France

  • Heinrich-Heine Universitätsklinik Düsseldorf

    Düsseldorf, 40225, Germany

  • Henry Ford Health System

    West Bloomfield, Michigan, 48322, United States

  • Hopital Gabriel Montpied

    Clermont-Ferrand, 63003, France

  • Hopital Henri Mondor

    Créteil, 94010, France

  • Hopital Pitie-Salpetriere APHP

    Paris, 75013, France

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital General de Catalunya

    Sant Cugat del Vallès, Barcelona, 08195, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen Macarena

    Seville, 41009, Spain

  • Hospital Universitario de la Princesa

    Madrid, 28006, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08025, Spain

  • Hôpital Michallon - Centre d'Investigation Clinique

    Grenoble, 38043, France

  • Klinik fur Neurologie

    Berlin, 10117, Germany

  • Klinik und Poliklinik für Neurologie Universitätsklinikum

    Leipzig, 04103, Germany

  • Medizinische Universität Innsbruck

    Innsbruck, 6020, Austria

  • Molecular Neurolmaging

    New Haven, Connecticut, 06510, United States

  • Neurology Center of North Orange County

    Fullerton, California, 92835, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Oregon Health & Science Uni

    Portland, Oregon, 97239, United States

  • Paracelsus Elena Klinik Kassel

    Kassel, 34128, Germany

  • Parkinson's Disease and Movement Disorders Center of Boca Raton

    Boca Raton, Florida, 33486, United States

  • Philipps Universität Marburg

    Marburg, 35043, Germany

  • Policlínica Guipuzcoa

    Donostia / San Sebastian, Guipuzcoa, 20014, Spain

  • Quest Research Institute

    Farmington Hills, Michigan, 48334, United States

  • The Movement Disorder Clinic of Oklahoma

    Tulsa, Oklahoma, 74136, United States

  • UNIVERSITY of PENNSYLVANIA

    Philadelphia, Pennsylvania, 19107, United States

  • USC Keck Medical Center of USC

    Los Angeles, California, 90033, United States

  • USF Parkinsons Disease and Movement Disorders Center

    Tampa, Florida, 33613, United States

  • Uab Medicine

    Birmingham, Alabama, 35233, United States

  • Universitaettsklinikum Tübingen

    Tübingen, 72076, Germany

  • University of California at San Francisco

    San Francisco, California, 94115, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Rochester Medical Center

    Rochester, New York, 14618, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • hopital de la Timone

    Marseille, 13385, France

Conditions

Explore the condition pages connected to this study.