Major trial tests first drug aimed at slowing Parkinson's itself

NCT ID NCT07174310

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether a new intravenous drug called prasinezumab can slow the worsening of movement problems in people with early Parkinson's disease. It will compare the drug against a placebo in 900 participants who are already on a stable dose of standard Parkinson's medication. The main goal is to see if the treatment can delay the progression of motor symptoms like tremors and stiffness.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aarhus Universitetshospital Skejby
RECRUITING

Aarhus N, 8200, Denmark
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Az. Osp. OO.RR. S. Giovanni di Dio e Ruggi D' Aragona
RECRUITING

Salerno, Campania, 84131, Italy
Beijing Friendship Hospital Affiliated of Capital University of Medical Science
RECRUITING

Beijing, 100050, China
Bispebjerg Hospital;Neurologisk Afdeling
RECRUITING

København NV, 2400, Denmark
CHUM
RECRUITING

Montreal, Quebec, H2X 0A9, Canada
CNS - Campus Neurológico
RECRUITING

Torres Vedras, 2560-280, Portugal
Campus for Ageing and Vitality
RECRUITING

Newcastle, NE4 5PL, United Kingdom
Central Texas Neurology Consultants
RECRUITING

Round Rock, Texas, 78681, United States
Centro de Pesquisas Clinicas
RECRUITING

São Paulo, São Paulo, 01228-200, Brazil
Changhua Christian Hospital
RECRUITING

Changhua County, 500, Taiwan
Charing Cross Hospital
RECRUITING

London, W6 8RF, United Kingdom
Charter Research - Winter Park/Orlando
RECRUITING

Orlando, Florida, 32803, United States
China Medical University Hospital
RECRUITING

North Dist., 40447, Taiwan
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Dent Neurological Institute
RECRUITING

Amherst, New York, 14226, United States
Fujian Medical University Union Hospital
RECRUITING

Fuzhou, 350001, China
Hawaii Pacific Neuroscience
RECRUITING

Honolulu, Hawaii, 96817, United States
Heinrich-Heine Universitätsklinik Düsseldorf
RECRUITING

Düsseldorf, 40225, Germany
Hospital Clinic Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Dr. Nélio Mendonça;Serviço de Neurologia
RECRUITING

Funchal, 9004-514, Portugal
Hospital General De Catalunya
RECRUITING

Sant Cugat del Vallès, Barcelona, 08195, Spain
Hospital General de Mexico
RECRUITING

Mexico City, Mexico CITY (federal District), 6726, Mexico
Hospital Pedro Hispano
RECRUITING

Matosinhos Municipality, 4464-513, Portugal
Hospital Quiron de Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hospital Ruber Juan Bravo
RECRUITING

Madrid, 28006, Spain
Hospital Univ 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario Fundación Alcorcón
RECRUITING

Alcorcón, Madrid, 28922, Spain
Hospital Universitario de La Princesa
RECRUITING

Madrid, 28006, Spain
Hospital da Luz Coimbra
RECRUITING

Coimbra, 3020-479, Portugal
Hospital de Braga
RECRUITING

Braga, 4710-243, Portugal
IRCCS Istituto Neurologico Carlo Besta
RECRUITING

Milan, Lombardy, 20133, Italy
Indywidualna Praktyka Lekarska Prof. Dr Hab. N. Med. Konrad Rejdak.
RECRUITING

Lublin, 20-410, Poland
Institute for Neurodegenerative Disorders
RECRUITING

New Haven, Connecticut, 06510, United States
Instituto de Neurologia de Curitiba
RECRUITING

Curitiba, Paraná, 81210-310, Brazil
Instytut Zdrowia Dr Boczarska-Jedynak Sp. z o.o. Sp. k.
RECRUITING

Oświęcim, 32-600, Poland
Irccs A.O.U.San Martino Ist
RECRUITING

Genoa, Liguria, 16132, Italy
JEM Research LLC
RECRUITING

Atlantis, Florida, 33462, United States
K2 - Villages
RECRUITING

Lady Lake, Florida, 32159, United States
K2 Medical Research-Maitland
RECRUITING

Maitland, Florida, 32751, United States
Keck School of Medicine of USC
RECRUITING

Los Angeles, California, 900033, United States
Kepler Universitätsklinikum GmbH - Neuromed Campus
RECRUITING

Linz, 4020, Austria
Klinik Ottakring
RECRUITING

Vienna, 1160, Austria
Klinikum rechts der Isar der TU München
RECRUITING

Munich, 81675, Germany
Krakowska Akademia Neurologii Sp z o.o. Centrum Neurologii K
RECRUITING

Krakow, 31-505, Poland
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mazowiecki Szpital Bródnowski w Warszawie Sp. z o.o.
RECRUITING

Warsaw, 03-242, Poland
Medizinische Universität Graz
RECRUITING

Graz, 8036, Austria
Monash Health
RECRUITING

Clayton, Victoria, 3168, Australia
Montreal Neurological Institute and Hospital
RECRUITING

Montreal, Quebec, H3A 2B4, Canada
NEURO-CARE Sp. z o.o. Sp. Komandytowa
RECRUITING

Katowice, 40-749, Poland
NZOZ Vitamed
RECRUITING

Bydgoszcz, 85-079, Poland
Nanjing Brain Hospital
RECRUITING

Nanjing, 210029, China
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan
NeuroCare Center
RECRUITING

Canton, Ohio, 44718, United States
NeuroProtect
RECRUITING

Warsaw, 01-684, Poland
Neurology Center of North Orange County
RECRUITING

Fullerton, California, 92835, United States
Ninewells Hospital, Dundee- Scotland
RECRUITING

Dundee, DD2 1SY, United Kingdom
Nmedis sp. z o.o.
RECRUITING

Rzeszów, 35-232, Poland
Núcleo de Pesquisa do Rio Grande do Sul
RECRUITING

Porto Alegre, Rio Grande do Sul, 90430-001, Brazil
Oxford University Hospitals NHS Foundation Trust
RECRUITING

Oxford, OX3 7LE, United Kingdom
Paracelsus Elena Klinik Kassel
RECRUITING

Kassel, 34128, Germany
Parkinson's Disease and Movement Disorders Center of Boca Raton
RECRUITING

Boca Raton, Florida, 33486, United States
Parkinson's Research Centers of America - Long Island
RECRUITING

Commack, New York, 11725, United States
Parkinson?s Research Centers of America ? Palo Alto
RECRUITING

Palo Alto, California, 94301, United States
Perron Institute for Neurological and Translational Science
RECRUITING

Nedlands, Western Australia, 6009, Australia
Plymouth Hospitals NHS Trust - Derriford Hospital
RECRUITING

Plymouth,Devon, PL6 8DH, United Kingdom
Podlaskie Centrum Psychogeriatrii
RECRUITING

Bia?ystok, 15-756, Poland
Policlinica Guipuzcoa
RECRUITING

Donostia / San Sebastian, Guipuzcoa, 20009, Spain
Profound Research LLC at The Neurology Center of Southern California
RECRUITING

Pasadena, California, 91105, United States
Quest Research Institute
RECRUITING

Farmington Hills, Michigan, 48334, United States
Renown Health
RECRUITING

Reno, Nevada, 89502, United States
Rocky Mountain Movement Disorders
RECRUITING

Englewood, Colorado, 80113, United States
Royal Devon and Exeter Hospital (Wonford)
RECRUITING

Exeter, EX2 5DW, United Kingdom
Royal London Hospital
RECRUITING

London, E1 1FR, United Kingdom
Seoul National University Hospital
RECRUITING

Seoul, 110-744, South Korea
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Southern Neurology
RECRUITING

Kogarah, New South Wales, 2217, Australia
Szpital Sw. Wojciecha
RECRUITING

Gda?sk, 80-462, Poland
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Texas Neurology PA
RECRUITING

Dallas, Texas, 75206, United States
The Alfred Hospital
RECRUITING

Prahan, Victoria, 3181, Australia
The First Affiliated Hospital of Sun Yat-sen University
RECRUITING

Guangzhou, 510080, China
The First Affiliated Hospital, Chongqing Medical University
RECRUITING

Chongqing, 400016, China
The First Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Movement Disorder Clinic of Oklahoma
RECRUITING

Tulsa, Oklahoma, 74136, United States
The Second Affiliated Hospital of Suzhou University
RECRUITING

Suzhou, 215025, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310009, China
UCSF Weill Institute for Neurosciences
RECRUITING

San Francisco, California, 94158, United States
Uniklinik fuer Neurologie, Medizinische Universitaet Innsbruck
RECRUITING

Innsbruck, 6020, Austria
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Virginia Health System
RECRUITING

Charlottesville, Virginia, 22903, United States
Università degli studi della Campania Luigi Vanvitelli
RECRUITING

Naples, Campania, 80138, Italy
Universitätsklinikum Erlangen, Abteilung Molekulare Neurologie
RECRUITING

Erlangen, 91054, Germany
Veracity Neuroscience
RECRUITING

Memphis, Tennessee, 38157, United States
Washington Uni School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Weill Cornell Medical College
RECRUITING

New York, New York, 10021, United States
West China Hospital of Sichuan University
RECRUITING

Chengdu, 610041, China
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.

PARKINSON'S DISEASE