Parkinson's biomarker hunt: sargramostim trial seeks clues in immune cells

NCT ID NCT05677633

First seen Nov 05, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-phase study tested a drug called sargramostim (Leukine) in 11 people with Parkinson's disease to see if it is safe and to find biological markers (biomarkers) in immune cells that could show how the drug works. Participants received the drug weekly for 48 weeks and had regular blood tests and leukapheresis to collect immune cells. The goal was to understand immune changes linked to Parkinson's, not to cure or treat symptoms directly.

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Contacts and locations

Locations

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

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